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PROTEIN-MEDIATED ACTOMYOSIN DYNAMICS
My group and other members of the CTBP have developed a novel theoretical and computational approach of understanding the structural plasticity of a dendritic spine based on the framework of far-from equilibrium physics. We focus on how the upstream calmodulin-dependent calcium signaling triggers the remodeling of actomyosin networks, a key component of cytoskeleton, that leads to the morphological change in a dendritic spine in neuronal cells, which influences learning and memory formation.
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