2006-2011

M. S. Cheung, D. Thirumalai, “Nanopore-protein interactions dramatically alter stability and yield of the native state in restricted spaces”, J. Mol. Biol., 357, 632-643 (2006).

M. E. Sardiu, M. S. Cheung, Y.-K. Yu, “Cysteine-Cysteine contact preference leads to target-focusing in protein folding”, Biophys., J., 93, 1-14 (2007).

M. S. Cheung, D. Thirumalai, “Crowding and confinement effects on structures of the transition state ensemble in proteins”, J. Phys. Chem. B, 111, 8250-8257 (2007).

S.-Q. Zhang, M. S. Cheung, “Manipulating Biopolymer Dynamics by Anisotropic Nanoconfinement”, Nano Letters, 7, 3438-3442 (2007).

· This paper is in Research Highlights, Nature Nanotechnology 2007

L. Stagg, S.-Q. Zhang, M. S. Cheung, P. Wittung-Stafshede, “Molecular crowding enhances native structure and stability of α/β protein flavodoxin”, Proc. Natl. Acad. Sci. U. S. A., 104, 18976-18981 (2007).

D. Homouz, M. Perham, A. Samiotakis, M. S. Cheung, P. Wittung-Stafshede. “Crowded, cell-like environment induces shape changes in aspherical protein”, Proc. Natl. Acad. Sci. U. S. A., 105, 11754-11759 (2008).

· Featured in Chemical & Engineering News, Aug 18th 08, issue

· Featured in Research Highlights in Nature (vol 454, p21, 2008).

· Featured as best biophysics paper in Research Highlights of 2008 in Nature.

D. Homouz, L. Stagg, P. Wittung-Stafshede, M. S. Cheung, “Macromolecular crowding modulates folding mechanism of α/β protein apoflavodoxin”, Biophys. J., 96, 671-680 (2009).

A. Samiotakis, P. Wittung-Stafshede, M. S. Cheung, “Folding, stability and shape of proteins in crowded environments: Experimental and computational approaches”, Int. J. Mol. Sci., 10, 572-588 (2009).

A. Kudlay, M. S. Cheung, D. Thirumalai, “Crowding effects on the structural transitions in a flexible helical homopolymer”, Phys. Rev. Letts., 102, 118101 (2009).

D. Homouz, B. Hoffman, M. S. Cheung, “Hydrophobic interactions of hexane in nanosized water droplets”, J. Phys. Chem. B, 113, 12337-12342 (2009).

· Byron Hoffman was an undergraduate from the Department of Physics, UH.

D. Homouz, H. Sanabria, M. N. Waxham, M. S. Cheung, “Modulation of calmodulin plasticity by the effect of macromolecular crowding”, J. Mol. Biol., 391, 933-943 (2009)

L. Stagg, A. Samiotakis, M. S. Cheung, P. Wittung-Stafshede, “Residue specific analysis of frustration in folding landscape of repeat β/α protein apoflavodoxin”, J. Mol. Biol., 396, 75-89 (2010).

A. Dhar, A. Samiotakis, S. Ebbinghaus, L. Nienhaus, D. Homouz, M. Gruebele, M. S. Cheung, "Structure, function and folding of phosphoglycerate kinase are strongly perturbed by macromolecular crowding", Proc. Natl. Acad. Sci. U. S. A., 107, 17586-17591 (2010).

· Commentary "Crowding and Function Reunite" by G. J. Pielak and A. C. Miklos, PNAS, 107, 17457-17458 (2010).

· Featured in the Cover Story "Tight Quarters" in Chemical & Engineering News, Nov 29th, 2010 issue.

· Featured in the UH Press release.

· Featured in local newspaper Lake Houston Observer.

· Featured in the Virtual Journal of Biological Physics Research.

· Featured in the Chinese Newspaper World Journal, North America Edition.

A. Samiotakis, D. Homouz, M. S. Cheung, "Multiscale investigation of chemical interference in proteins", J. Chem. Phys., 132, 175101 (2010).

· Featured by the Virtual Journal of Biological Physics Research

A. Christiansen, Q. Wang, A. Samiotakis, M. S. Cheung, P. Wittung-Stafshede, "Factors defining effects of macromolecular crowding on protein stability: an in vitro/in silico case study using cytochrome c", Biochemistry, 49, 6519-6530 (2010).

Q. Wang, G. Hong, J. Glenn, R. Pachter, M. S. Cheung, "Biophysical properties of membrane-active peptides based on micelle modeling: A case study of cell-penetrating and antimicrobial peptides", J. Phys. Chem. B, 114, 13726-13735 (2010).

Q. Wang, K.-C. Liang, A. Czader, M. N. Waxham, M. S. Cheung, "The effect of macromolecular crowding, ionic strength and calcium binding on calmodulin dynamics", PLoS Comp. Biol., 7, e1002114 (2011).

A. Samiotakis, M. S. Cheung, "Part I. Folding dynamics of Trp-cage in the presence of chemical interference and macromolecular crowding", J. Chem. Phys., 135, 175101 (2011).

  • Featured by the Virtual Journal of Biological Physics Research

Q. Wang, A. Christiansen, A. Samiotakis, P. Wittung-Stafshede, M. S. Cheung, “Part II. Comparison of chemical and thermal protein denaturation by combination of computational and experimental approaches", J. Chem. Phys., 135, 175102 (2011).

  • Featured by the Virtual Journal of Biological Physics Research